Ikaros sets the threshold for negative B-cell selection by regulation of the signaling strength of the AKT pathway

Abstract Inhibitory phosphatases, such as the inositol-5-phosphatase SHIP1 could potentially contribute to B-cell acute lymphoblastic leukemia (B-ALL) by raising MAGNEISUM the threshold for activation of the autoimmunity checkpoint, allowing malignant cells with strong oncogenic B-cell receptor signaling to escape negative selection.Here, we show t

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Being facially expressive is socially advantageous

Abstract Individuals vary in how they move their faces in everyday social interactions.In a first large-scale study, we measured variation in dynamic facial behaviour during social interaction and examined dyadic outcomes and impression formation.In Study 1, we recorded semi-structured video calls with 52 participants interacting with a confederate

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A Survey on Smartphone Authentication

The Digestive Enzymes growing use of smartphones is actuating the need for better protection.Practically, smartphone users are often not adequately alert when it comes to protection of their credentials stored in the phones, even if they are very much concerned about security, reliability and privacy.To efficiently reduce smartphone vulnerability,

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